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The Bromodomain Inhibitor, INCB057643, Targets Both Cancer Cells and the Tumor Microenvironment in Two Preclinical Models of Pancreatic Cancer

SIMPLE SUMMARY: Pancreatic cancer remains a highly lethal disease, with only ~10% of patients still alive five years after diagnosis, as most patients already have advanced, metastatic disease at the time of diagnosis. Therefore, new treatments are needed for these patients. We tested INCB057643, a...

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Podrobná bibliografie
Vydáno v:Cancers (Basel)
Hlavní autoři: Leal, Ana S., Liu, Phillip, Krieger-Burke, Teresa, Ruggeri, Bruce, Liby, Karen T.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794921/
https://ncbi.nlm.nih.gov/pubmed/33396954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13010096
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