An autophagy enhancer ameliorates diabetes of human IAPP-transgenic mice through clearance of amyloidogenic oligomer

We have reported that autophagy is crucial for clearance of amyloidogenic human IAPP (hIAPP) oligomer, suggesting that an autophagy enhancer could be a therapeutic modality against human diabetes with amyloid accumulation. Here, we show that a recently identified autophagy enhancer (MSL-7) reduces h...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kim, Jinyoung, Park, Kihyoun, Kim, Min Jung, Lim, Hyejin, Kim, Kook Hwan, Kim, Sun-Woo, Lee, Eun-Seo, Kim, Hyongbum (Henry), Kim, Sung Joo, Hur, Kyu Yeon, Kim, Jae Hyeon, Ahn, Jin Hee, Yoon, Kun-Ho, Kim, Ji-Won, Lee, Myung-Shik
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794419/
https://ncbi.nlm.nih.gov/pubmed/33420039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20454-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados