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Microvessel occlusions alter amyloid-beta plaque morphology in a mouse model of Alzheimer’s disease

Vascular dysfunction is correlated to the incidence and severity of Alzheimer’s disease. In a mouse model of Alzheimer’s disease (APP/PS1) using in vivo, time-lapse, multiphoton microscopy, we found that occlusions of the microvasculature alter amyloid-beta (Aβ) plaques. We used several models of va...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cereb Blood Flow Metab
Hauptverfasser: Zhang, Yuying, Bander, Evan D, Lee, Yurim, Muoser, Celia, Schaffer, Chris B, Nishimura, Nozomi
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7786844/
https://ncbi.nlm.nih.gov/pubmed/31744388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X19889092
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