Human skin is colonized by T cells that recognize CD1a independently of lipid

CD1a-autoreactive T cells contribute to skin disease, but the identity of immunodominant self-lipid antigens and their mode of recognition are not yet solved. In most models, MHC and CD1 proteins serve as display platforms for smaller antigens. Here, we showed that CD1a tetramers without added antig...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Clin Invest
Κύριοι συγγραφείς: Cotton, Rachel N., Cheng, Tan-Yun, Wegrecki, Marcin, Le Nours, Jérôme, Orgill, Dennis P., Pomahac, Bohdan, Talbot, Simon G., Willis, Richard A., Altman, John D., de Jong, Annemieke, Ogg, Graham, Van Rhijn, Ildiko, Rossjohn, Jamie, Clark, Rachael A., Moody, D. Branch
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2021
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773353/
https://ncbi.nlm.nih.gov/pubmed/33393500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI140706
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια