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Distinct Effects of Inflammation on Cytochrome P450 Regulation and Drug Metabolism: Lessons from Experimental Models and a Potential Role for Pharmacogenetics

Personalized medicine strives to optimize drug treatment for the individual patient by taking into account both genetic and non-genetic factors for drug response. Inflammation is one of the non-genetic factors that has been shown to greatly affect the metabolism of drugs—primarily through inhibition...

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Bibliografiske detaljer
Udgivet i:Genes (Basel)
Main Authors: de Jong, Laura M., Jiskoot, Wim, Swen, Jesse J., Manson, Martijn L.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7766585/
https://ncbi.nlm.nih.gov/pubmed/33339226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11121509
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