Pharmacological blockade of TNFα prevents sarcopenia and prolongs survival in aging mice

Sarcopenia is a hallmark of aging. Inflammation due to increased generation of cytokines such as TNFα, IL-1β and IL-6 has been implicated in the pathogenesis of sarcopenia. In skeletal muscle of C57BL/6 mice from 12 until 28 months of age, we observed a progressive reduction of myofiber cross sectio...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Aging (Albany NY)
Main Authors: Sciorati, Clara, Gamberale, Riccardo, Monno, Antonella, Citterio, Lorena, Lanzani, Chiara, De Lorenzo, Rebecca, Ramirez, Giuseppe A., Esposito, Antonio, Manunta, Paolo, Manfredi, Angelo A., Rovere-Querini, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals 2020
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762456/
https://ncbi.nlm.nih.gov/pubmed/33260150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202200
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares