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Exosomes from Bone Marrow Microenvironment-Derived Mesenchymal Stem Cells Affect CML Cells Growth and Promote Drug Resistance to Tyrosine Kinase Inhibitors

Although major advances have been achieved in the treatment of chronic myeloid leukemia (CML) by using tyrosine kinase inhibitors, patients relapse after withdrawal and need long-term medication. This reflects the CML clones have not been eliminated completely. The precise mechanisms for the mainten...

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Bibliografische gegevens
Gepubliceerd in:Stem Cells Int
Hoofdauteurs: Zhang, Xiaoyan, Yang, Yazhi, Yang, Yang, Chen, Huijun, Tu, Huaijun, Li, Jian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752271/
https://ncbi.nlm.nih.gov/pubmed/33414831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8890201
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