Exosomes from Bone Marrow Microenvironment-Derived Mesenchymal Stem Cells Affect CML Cells Growth and Promote Drug Resistance to Tyrosine Kinase Inhibitors

Although major advances have been achieved in the treatment of chronic myeloid leukemia (CML) by using tyrosine kinase inhibitors, patients relapse after withdrawal and need long-term medication. This reflects the CML clones have not been eliminated completely. The precise mechanisms for the mainten...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Stem Cells Int
Autori principali: Zhang, Xiaoyan, Yang, Yazhi, Yang, Yang, Chen, Huijun, Tu, Huaijun, Li, Jian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2020
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752271/
https://ncbi.nlm.nih.gov/pubmed/33414831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8890201
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