Inhibition of SETMAR–H3K36me2–NHEJ repair axis in residual disease cells prevents glioblastoma recurrence

BACKGROUND: Residual disease of glioblastoma (GBM) causes recurrence. However, targeting residual cells has failed, due to their inaccessibility and our lack of understanding of their survival mechanisms to radiation therapy. Here we deciphered a residual cell–specific survival mechanism essential f...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Kaur, Ekjot, Nair, Jyothi, Ghorai, Atanu, Mishra, Saket V, Achareker, Anagha, Ketkar, Madhura, Sarkar, Debashmita, Salunkhe, Sameer, Rajendra, Jacinth, Gardi, Nilesh, Desai, Sanket, Iyer, Prajish, Thorat, Rahul, Dutt, Amit, Moiyadi, Aliasgar, Dutt, Shilpee
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7746947/
https://ncbi.nlm.nih.gov/pubmed/32458986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa128
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