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Emergence of a high-plasticity cell state during lung cancer evolution
Tumor evolution from a single cell into a malignant, heterogeneous tissue remains poorly understood. Here, we profile single-cell transcriptomes of genetically engineered mouse lung tumors at seven stages, from pre-neoplastic hyperplasia to adenocarcinoma. The diversity of transcriptional states inc...
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| Yayımlandı: | Cancer Cell |
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7745838/ https://ncbi.nlm.nih.gov/pubmed/32707077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2020.06.012 |
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