Overexpression of SARS-CoV-2 protein ORF6 dislocates RAE1 and NUP98 from the nuclear pore complex

The novel human betacoronavirus SARS-CoV-2 has caused an unprecedented pandemic in the 21st century. Several studies have revealed interactions between SARS-CoV-2 viral proteins and host nucleoporins, yet their functions are largely unknown. Here, we demonstrate that the open-reading frame 6 (ORF6)...

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Vydáno v:Biochem Biophys Res Commun
Hlavní autoři: Kato, Koki, Ikliptikawati, Dini Kurnia, Kobayashi, Akiko, Kondo, Hiroya, Lim, Keesiang, Hazawa, Masaharu, Wong, Richard W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Inc. 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733692/
https://ncbi.nlm.nih.gov/pubmed/33360543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.11.115
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