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Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload
The inhibitory Smad7 acts as a critical suppressor of hepcidin, the major regulator of systemic iron homeostasis. In this study we define the mRNA expression of the two functionally related Smad proteins, Smad6 and Smad7, within pathways known to regulate hepcidin levels. Using mouse models for here...
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| Veröffentlicht in: | Biochim Biophys Acta |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7731909/ https://ncbi.nlm.nih.gov/pubmed/22960056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.08.013 |
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