Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload

The inhibitory Smad7 acts as a critical suppressor of hepcidin, the major regulator of systemic iron homeostasis. In this study we define the mRNA expression of the two functionally related Smad proteins, Smad6 and Smad7, within pathways known to regulate hepcidin levels. Using mouse models for here...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochim Biophys Acta
Prif Awduron: Spasić, Maja Vujić, Sparla, Richard, Mleczko-Sanecka, Katarzyna, Migas, Mary C., Breitkopf-Heinlein, Katja, Dooley, Steven, Vaulont, Sophie, Fleming, Robert E., Muckenthaler, Martina U.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7731909/
https://ncbi.nlm.nih.gov/pubmed/22960056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.08.013
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