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Triangular Relationship between p53, Autophagy, and Chemotherapy Resistance

Chemotherapy and radiation often induce a number of cellular responses, such as apoptosis, autophagy, and senescence. One of the major regulators of these processes is p53, an essential tumor suppressor that is often mutated or lost in many cancer types and implicated in early tumorigenesis. Gain of...

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Pubblicato in:Int J Mol Sci
Autori principali: Xu, Jingwen, Patel, Nipa H., Gewirtz, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730978/
https://ncbi.nlm.nih.gov/pubmed/33256191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21238991
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