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Synthesis and in Silico Modelling of the Potential Dual Mechanistic Activity of Small Cationic Peptides Potentiating the Antibiotic Novobiocin against Susceptible and Multi-Drug Resistant Escherichia coli

Cationic antimicrobial peptides have attracted interest, both as antimicrobial agents and for their ability to increase cell permeability to potentiate other antibiotics. However, toxicity to mammalian cells and complexity have hindered development for clinical use. We present the design and synthes...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Int J Mol Sci
Main Authors: Passarini, Ilaria, de Resende, Pedro Ernesto, Soares, Sarah, Tahmasi, Tadeh, Stapleton, Paul, Malkinson, John, Zloh, Mire, Rossiter, Sharon
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730182/
https://ncbi.nlm.nih.gov/pubmed/33266278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239134
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