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Biological Properties of New Chiral 2-Methyl-5,6,7,8-tetrahydroquinolin-8-amine-based Compounds

The synthesis of a small library of 8-substituted 2-methyl-5,6,7,8-tetrahydroquinoline derivatives is presented. All the compounds were tested for their antiproliferative activity in non-cancer human dermal microvascular endothelial cells (HMEC-1) and cancer cells: human T-lymphocyte cells (CEM), hu...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Facchetti, Giorgio, Christodoulou, Michael S., Mendoza, Lina Barragán, Cusinato, Federico, Dalla Via, Lisa, Rimoldi, Isabella
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729733/
https://ncbi.nlm.nih.gov/pubmed/33260896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25235561
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