Blocking mitochondrial pyruvate import in brown adipocytes induces energy wasting via lipid cycling

Combined fatty acid esterification and lipolysis, termed lipid cycling, is an ATP‐consuming process that contributes to energy expenditure. Therefore, interventions that stimulate energy expenditure through lipid cycling are of great interest. Here we find that pharmacological and genetic inhibition...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Veliova, Michaela, Ferreira, Caroline M, Benador, Ilan Y, Jones, Anthony E, Mahdaviani, Kiana, Brownstein, Alexandra J, Desousa, Brandon R, Acín‐Pérez, Rebeca, Petcherski, Anton, Assali, Essam A, Stiles, Linsey, Divakaruni, Ajit S, Prentki, Marc, Corkey, Barbara E, Liesa, Marc, Oliveira, Marcus F, Shirihai, Orian S
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726774/
https://ncbi.nlm.nih.gov/pubmed/33275313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949634
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