Platelets Selectively Regulate the Release of BDNF, But Not That of Its Precursor Protein, proBDNF

BACKGROUND: Brain-derived neurotrophic factor (BDNF) plays a role in synaptic plasticity and neuroprotection. BDNF has well-established pro-survival effects, whereas its precursor protein, proBDNF, induces apoptosis. Thus, it has been suggested that the proBDNF/BDNF ratio could be an indicator of ne...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Le Blanc, Jessica, Fleury, Samuel, Boukhatem, Imane, Bélanger, Jean-Christophe, Welman, Mélanie, Lordkipanidzé, Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723927/
https://ncbi.nlm.nih.gov/pubmed/33324399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.575607
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