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Cleavage of hepatocyte growth factor activator inhibitor‐1 by membrane‐type MMP‐1 activates matriptase
Co‐expression of membrane‐type 1 (MT1)‐MMP with hepatocyte growth factor activator inhibitor‐1 (HAI‐1) in HEK293T cells resulted in cleavage of HAI‐1 to produce three fragments. Recombinant MT1‐MMP was shown to cleave HAI‐1 protein in vitro. Hepatocyte growth factor activator inhibitor‐1 was initial...
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| Publicado no: | Cancer Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7713627/ https://ncbi.nlm.nih.gov/pubmed/22118498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2011.02162.x |
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