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Increased prevalence of pfdhfr and pfdhps mutations associated with sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates from Jazan Region, Southwestern Saudi Arabia: important implications for malaria treatment policy

BACKGROUND: Despite significant progress in eliminating malaria from the Kingdom of Saudi Arabia, the disease is still endemic in the southwestern region of the country. Artesunate plus sulfadoxine–pyrimethamine (AS + SP) has been used in Saudi Arabia since 2007 as a first-line treatment for uncompl...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Madkhali, Aymen M., Al-Mekhlafi, Hesham M., Atroosh, Wahib M., Ghzwani, Ahmad Hassn, Zain, Khalid Ammash, Abdulhaq, Ahmed A., Ghailan, Khalid Y., Anwar, Alkhansa A., Eisa, Zaki M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709338/
https://ncbi.nlm.nih.gov/pubmed/33267841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-020-03524-x
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