Antimicrobial peptide AR‐23 derivatives with high endosomal disrupting ability enhance poly(l‐lysine)‐mediated gene transfer

BACKGROUND: pH‐sensitive peptides are a relatively new strategy for conquering the poor endosomal release of cationic polymer‐mediated transfection. Modification of antimicrobial peptides by exchanging positively‐charged residues with negatively‐charged glutamic acid residues (Glu) greatly improves...

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Detalhes bibliográficos
Publicado no:J Gene Med
Main Authors: Zhang, Shi‐Kun, Gong, Lin, Zhang, Xue, Yun, Zhi‐Min, Li, Su‐Bo, Gao, Hong‐Wei, Dai, Cong‐Jie, Yuan, Jian‐Jun, Chen, Jing‐Ming, Gong, Feng, Tan, Ying‐Xia, Ji, Shou‐Ping
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685122/
https://ncbi.nlm.nih.gov/pubmed/32776410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.3259
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