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Predictive and Prognostic Value of DNA Damage Response Associated Kinases in Solid Tumors
Dysfunctional DNA repair with subsequent genome instability and high mutational burden represents a major hallmark of cancer. In established malignant tumors, increased DNA repair capacity mediates resistance to DNA-damaging therapeutics, including cytotoxic drugs, radiotherapy, and selected small m...
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| Publicado no: | Front Oncol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7670868/ https://ncbi.nlm.nih.gov/pubmed/33224881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.581217 |
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