Distinguishing Features of High and Low Dose Vaccine Against Ocular HSV-1 Infection Correlates with Recognition of Specific HSV-1-Encoded Proteins

The protective efficacy of a live attenuated herpes simplex virus type 1 (HSV-1) vaccine, HSV-1 0ΔNLS, was evaluated in mice prophylactically in response to ocular HSV-1 challenge. Mice vaccinated with the HSV-1 0ΔNLS were found to be more resistant to subsequent ocular virus challenge in terms of v...

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Veröffentlicht in:Immunohorizons
Hauptverfasser: Carr, Daniel J.J., Gmyrek, Grzegorz B., Filiberti, Adrian, Berube, Amanda N., Browne, William P., Gudgel, Brett M., Sjoelund, Virginie H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668388/
https://ncbi.nlm.nih.gov/pubmed/33037098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/immunohorizons.2000060
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