Physiologic RNA targets and refined sequence specificity of coronavirus EndoU

Coronavirus EndoU inhibits dsRNA-activated antiviral responses; however, the physiologic RNA substrates of EndoU are unknown. In this study, we used mouse hepatitis virus (MHV)-infected bone marrow–derived macrophage (BMM) and cyclic phosphate cDNA sequencing to identify the RNA targets of EndoU. En...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Ancar, Rachel, Li, Yize, Kindler, Eveline, Cooper, Daphne A., Ransom, Monica, Thiel, Volker, Weiss, Susan R., Hesselberth, Jay R., Barton, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668261/
https://ncbi.nlm.nih.gov/pubmed/32989044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.076604.120
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