Sialylation of Asparagine 612 Inhibits Aconitase Activity during Mouse Sperm Capacitation; a Possible Mechanism for the Switch from Oxidative Phosphorylation to Glycolysis

After ejaculation, mammalian spermatozoa must undergo a process known as capacitation in order to successfully fertilize the oocyte. Several post-translational modifications occur during capacitation, including sialylation, which despite being limited to a few proteins, seems to be essential for pro...

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Bibliographic Details
Published in:Mol Cell Proteomics
Main Authors: Silva Balbin Villaverde, Ana Izabel, Ogle, Rachel A., Lewis, Peter, Carbone, Vincenzo, Velkov, Tony, Netherton, Jacob K., Baker, Mark A.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2020
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7664118/
https://ncbi.nlm.nih.gov/pubmed/32839225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA120.002109
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