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Tumor microvasculature with endothelial fenestrations in VHL null clear cell renal cell carcinomas as a potent target of anti‐angiogenic therapy

Vascular endothelial growth factor (VEGF)‐targeted therapies show significant antitumor effects for advanced clear cell renal cell carcinomas (CC‐RCCs). Previous studies using VEGF inhibitors in mice models revealed that VEGF‐dependent capillaries were characterized by the existence of endothelial f...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Yamasaki, Toshinari, Kamba, Tomomi, Kanno, Toru, Inoue, Takahiro, Shibasaki, Noboru, Arakaki, Ryuichiro, Yamada, Tomomi, Kondo, Keiichi, Kamoto, Toshiyuki, Nishiyama, Hiroyuki, Ogawa, Osamu, Nakamura, Eijiro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7659343/
https://ncbi.nlm.nih.gov/pubmed/22931246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02412.x
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