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Effect of drug dose and timing of treatment on the emergence of drug resistance in vivo in a malaria model

BACKGROUND AND OBJECTIVES: There is a significant interest in identifying clinically effective drug treatment regimens that minimize the de novo evolution of antimicrobial resistance in pathogen populations. However, in vivo studies that vary treatment regimens and directly measure drug resistance e...

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Bibliographic Details
Published in:Evol Med Public Health
Main Authors: Acosta, Mónica M, Bram, Joshua T, Sim, Derek, Read, Andrew F
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652304/
https://ncbi.nlm.nih.gov/pubmed/33209305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emph/eoaa016
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