Lactate dehydrogenase A inhibition by small molecular entities: steps in the right direction

Direct targeting of energy metabolism to defeat cancer is not a recent strategy. Although quite a few drugs use cellular metabolism for their antitumor effect, no direct inhibitors of energy metabolism have been approved by the FDA. Currently, several inhibitors of lactate dehydrogenase A (LDH-A), a...

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Detalhes bibliográficos
Publicado no:Oncoscience
Main Authors: El Hassouni, Btissame, Franczak, Marika, Capula, Mjriam, Vonk, Christian M., Gomez, Valentina M., Smolenski, Ryszard T., Granchi, Carlotta, Peters, Godefridus J., Minutolo, Filippo, Giovannetti, Elisa
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Research Perspective
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7640902/
https://ncbi.nlm.nih.gov/pubmed/33195739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncoscience.519
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