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Polycystic kidney disease: The cilia mechanosensation debate gets (bio)physical
For the first time, two new studies applied a mechanical stimulus directly to a cilium, independent of a chemical signal, and demonstrated that force-based bending of a single nodal axoneme is sufficient to induce intraciliary Ca(2+) flux in a PKD2-dependent manner, which propagated to drive asymmet...
Shranjeno v:
| izdano v: | Nat Rev Nephrol |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2023
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614964/ https://ncbi.nlm.nih.gov/pubmed/36914889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41581-023-00701-4 |
| Oznake: |
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