p53 immunohistochemistry in endometrial cancer: clinical and molecular correlates in the PORTEC-3 trial

Standard molecular classification of endometrial cancers (EC) is now endorsed by the WHO and identifies p53-abnormal (p53abn) EC as the subgroup with the poorest prognosis and the most likely to benefit from adjuvant chemo(radio)therapy. P53abn EC are POLE wildtype, mismatch repair proficient and sh...

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Bibliografske podrobnosti
izdano v:Mod Pathol
Main Authors: Vermij, Lisa, Léon-Castillo, Alicia, Singh, Naveena, Powell, Melanie E., Edmondson, Richard J., Genestie, Catherine, Khaw, Pearly, Pyman, Jan, McLachlin, C. Meg, Ghatage, Prafull, de Boer, Stephanie M., Nijman, Hans W., Smit, Vincent T. H. B. M., Crosbie, Emma J., Leary, Alexandra, Creutzberg, Carien L., Horeweg, Nanda, Bosse, Tjalling
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group US 2022
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613653/
https://ncbi.nlm.nih.gov/pubmed/35752743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41379-022-01102-x
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