Comparative studies of renin-null zebrafish and mice provide new functional insights

BACKGROUND: The renin-angiotensin system (RAS) is highly conserved across vertebrates, including zebrafish, which possess orthologous genes coding for RAS proteins, and specialised mural cells of the kidney arterioles, capable of synthesising and secreting renin. METHODS: We generated zebrafish with...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Hoffmann, Scott, Mullins, Linda, Rider, Sebastien, Brown, Cara, Buckley, Charlotte B., Assmus, Adrienne, Li, Ziwen, Beltran, Mariana Sierra, Henderson, Neil, del Pozo, Jorge, De Goes Martini, Alexandre, Sequeira-Lopez, Maria Luisa S., Gomez, R. Ariel, Mullins, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2022
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612355/
https://ncbi.nlm.nih.gov/pubmed/35000430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.121.18600
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