Comparative studies of renin-null zebrafish and mice provide new functional insights

BACKGROUND: The renin-angiotensin system (RAS) is highly conserved across vertebrates, including zebrafish, which possess orthologous genes coding for RAS proteins, and specialised mural cells of the kidney arterioles, capable of synthesising and secreting renin. METHODS: We generated zebrafish with...

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Pubblicato in:Hypertension
Autori principali: Hoffmann, Scott, Mullins, Linda, Rider, Sebastien, Brown, Cara, Buckley, Charlotte B., Assmus, Adrienne, Li, Ziwen, Beltran, Mariana Sierra, Henderson, Neil, del Pozo, Jorge, De Goes Martini, Alexandre, Sequeira-Lopez, Maria Luisa S., Gomez, R. Ariel, Mullins, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2022
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612355/
https://ncbi.nlm.nih.gov/pubmed/35000430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.121.18600
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