Investigating higher order interactions in single cell data with scHOT

Single-cell genomics has transformed our ability to examine cell fate choice. Examining cells along a computationally ordered “pseudotime” offers the potential to unpick subtle changes in variability and covariation among key genes. We describe a novel approach, scHOT – single cell Higher Order Test...

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Udgivet i:Nat Methods
Main Authors: Ghazanfar, Shila, Lin, Yingxin, Su, Xianbin, Lin, David Ming, Patrick, Ellis, Han, Ze Guang, Marioni, John C., Yang, Jean Yee Hwa
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7610653/
https://ncbi.nlm.nih.gov/pubmed/32661426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-020-0885-x
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