Lipocalin-2 Exacerbates Lupus Nephritis by Promoting Th1 Cell Differentiation

BACKGROUND: Lipocalin-2 (LCN2) is an indicator of the severity of lupus nephritis (LN) and plays a pivotal role in immune responses, but it is not known if its effect on LN pathogenesis derives from regulating the immune imbalance of T lymphocyte subsets. METHODS: The expression of LCN2 in T cells a...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Chen, Weiwei, Li, Wenchao, Zhang, Zhuoya, Tang, Xiaojun, Wu, Shufang, Yao, Genhong, Li, Kang, Wang, Dandan, Xu, Yuemei, Feng, Ruihai, Duan, Xiaoxiao, Fan, Xiangshan, Lu, Liwei, Chen, WanJun, Li, Chaojun, Sun, Lingyun
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2020
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7609012/
https://ncbi.nlm.nih.gov/pubmed/32646856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019090937
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