Influence of Intratumor Heterogeneity on the Predictivity of MGMT Gene Promoter Methylation Status in Glioblastoma

Glioblastoma is the most aggressive tumor of the central nervous system. Prognosis is poor, even in the presence of a methylated state of MGMT gene promoter, which represents the biomarker with the highest prognostic/predictive value for the standard treatment of patients. Among patients with a meth...

Full description

Saved in:
Bibliographic Details
Published in:Front Oncol
Main Authors: Brigliadori, Giovanni, Goffredo, Giulia, Bartolini, Daniela, Tosatto, Luigino, Gurrieri, Lorena, Mercatali, Laura, Ibrahim, Toni
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606920/
https://ncbi.nlm.nih.gov/pubmed/33194592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.533000
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items