Antitumor Therapy under Hypoxic Microenvironment by the Combination of 2-Methoxyestradiol and Sodium Dichloroacetate on Human Non-Small-Cell Lung Cancer

A hypoxic microenvironment is a hallmark in different types of tumors; this phenomenon participates in a metabolic alteration that confers resistance to treatments. Because of this, it was proposed that a combination of 2-methoxyestradiol (2-ME) and sodium dichloroacetate (DCA) could reduce this alt...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Romero, Yair, Castillejos-López, Manuel, Romero-García, Susana, Aguayo, Alfonso Salgado, Herrera, Iliana, Garcia-Martin, Misael O., Torres-Espíndola, Luz Maria, Negrete-García, Maria Cristina, Olvera, Angel Camarena, Huerta-Cruz, Juan Carlos, Velázquez-Cruz, Rafael, Cisneros, José, Soto, Edgar Flores, Solís-Chagoyán, Héctor, Mendoza-Milla, Criselda, Cabello-Gutiérrez, Carlos, Ruiz, Víctor, Aquino-Gálvez, Arnoldo
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603622/
https://ncbi.nlm.nih.gov/pubmed/33149807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3176375
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