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Hippocampal Hyperactivity as a Druggable Circuit-Level Origin of Aberrant Salience in Schizophrenia
The development of current neuroleptics was largely aiming to decrease excessive dopaminergic signaling in the striatum. However, the notion that abnormal dopamine creates psychotic symptoms by causing an aberrant assignment of salience that drives maladaptive learning chronically during disease dev...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Front Pharmacol |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Frontiers Media S.A.
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7596262/ https://ncbi.nlm.nih.gov/pubmed/33178010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.486811 |
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