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Jagged1-Notch1-deployed tumor perivascular niche promotes breast cancer stem cell phenotype through Zeb1

Zinc finger E-box binding homeobox 1 (Zeb1) has been demonstrated to participate in the acquisition of the properties of cancer stem cells (CSCs). However, it is largely unknown how signals from the tumor microenvironment (TME) contribute to aberrant Zeb1 expression. Here, we show that Zeb1 depletio...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Jiang, Huimin, Zhou, Chen, Zhang, Zhen, Wang, Qiong, Wei, Huimin, Shi, Wen, Li, Jianjun, Wang, Zhaoyang, Ou, Yang, Wang, Wenhao, Wang, Hang, Zhang, Quansheng, Sun, Wei, Sun, Peiqing, Yang, Shuang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7552407/
https://ncbi.nlm.nih.gov/pubmed/33046710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18860-4
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