Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization

Many intestinal pathogens, including Clostridioides difficile, use mucus-derived sugars as crucial nutrients in the gut. Commensals that compete with pathogens for such nutrients are therefore ecological gatekeepers in healthy guts, and are attractive candidates for therapeutic interventions. Nevert...

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發表在:Nat Commun
Main Authors: Pereira, Fátima C., Wasmund, Kenneth, Cobankovic, Iva, Jehmlich, Nico, Herbold, Craig W., Lee, Kang Soo, Sziranyi, Barbara, Vesely, Cornelia, Decker, Thomas, Stocker, Roman, Warth, Benedikt, von Bergen, Martin, Wagner, Michael, Berry, David
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547075/
https://ncbi.nlm.nih.gov/pubmed/33037214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18928-1
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