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Enhanced Jarzynski free energy calculations using weighted ensemble

The free energy of transitions between stable states is the key thermodynamic quantity that governs the relative probabilities of the forward and reverse reactions and the ratio of state probabilities at equilibrium. The binding free energy of a drug and its receptor is of particular interest, as it...

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Detalhes bibliográficos
Publicado no:J Chem Phys
Main Authors: Roussey, Nicole M., Dickson, Alex
Formato: Artigo
Idioma:Inglês
Publicado em: AIP Publishing LLC 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7544513/
https://ncbi.nlm.nih.gov/pubmed/33032408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/5.0020600
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