Genetic variants in TKT and DERA in the NADPH pathway predict melanoma survival

BACKGROUND: Cutaneous melanoma (CM) is the most lethal type of skin cancers. Nicotinamide adenine dinucleotide phosphate (NADPH) plays an important role in anabolic reactions and tumorigenesis, but many genes are involved in the NADPH system. METHODS: We used 10,912 SNPs (2,018 genotyped and 8,894 i...

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Detalhes bibliográficos
Publicado no:Eur J Cancer
Main Authors: Gu, Ning, Dai, Wei, Liu, Hongliang, Ge, Jie, Luo, Sheng, Cho, Eunyoung, Amos, Christopher I., Lee, Jeffrey E., Li, Xin, Nan, Hongmei, Yuan, Hua, Wei, Qingyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540967/
https://ncbi.nlm.nih.gov/pubmed/32659474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2020.04.049
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