Genetic variants in TKT and DERA in the NADPH pathway predict melanoma survival

BACKGROUND: Cutaneous melanoma (CM) is the most lethal type of skin cancers. Nicotinamide adenine dinucleotide phosphate (NADPH) plays an important role in anabolic reactions and tumorigenesis, but many genes are involved in the NADPH system. METHODS: We used 10,912 SNPs (2,018 genotyped and 8,894 i...

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Bibliografiske detaljer
Udgivet i:Eur J Cancer
Main Authors: Gu, Ning, Dai, Wei, Liu, Hongliang, Ge, Jie, Luo, Sheng, Cho, Eunyoung, Amos, Christopher I., Lee, Jeffrey E., Li, Xin, Nan, Hongmei, Yuan, Hua, Wei, Qingyi
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540967/
https://ncbi.nlm.nih.gov/pubmed/32659474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2020.04.049
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