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Structure–function studies of Rgg binding to pheromones and target promoters reveal a model of transcription factor interplay

Regulator gene of glucosyltransferase (Rgg) family proteins, such as Rgg2 and Rgg3, have emerged as primary quorum-sensing regulated transcription factors in Streptococcus species, controlling virulence, antimicrobial resistance, and biofilm formation. Rgg2 and Rgg3 function is regulated by their in...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Capodagli, Glenn C., Tylor, Kaitlyn M., Kaelber, Jason T., Petrou, Vasileios I., Federle, Michael J., Neiditch, Matthew B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533842/
https://ncbi.nlm.nih.gov/pubmed/32907945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2008427117
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