Germline polymorphisms associated with impaired survival outcomes and somatic tumor alterations in advanced prostate cancer

INTRODUCTION: Germline variants in androgen metabolism genes may influence clinical response to androgen deprivation therapy (ADT) in advanced prostate cancer. We sought to investigate the prognostic significance of germline variants in androgen metabolism genes with respect to overall survival (OS)...

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Udgivet i:Prostate Cancer Prostatic Dis
Main Authors: Chen, William S., Feng, Eric, Aggarwal, Rahul, Foye, Adam, Beer, Tomasz M., Alumkal, Joshi J., Gleave, Martin, Chi, Kim N., Reiter, Robert E., Rettig, Matthew B., Evans, Christopher P., Small, Eric J., Sharifi, Nima, Zhao, Shuang G.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529063/
https://ncbi.nlm.nih.gov/pubmed/31745256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41391-019-0188-4
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