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Novel cytokinetic ring components drive negative feedback in cortical contractility

Actomyosin cortical contractility drives many cell shape changes including cytokinetic furrowing. While positive regulation of contractility is well characterized, counterbalancing negative regulation and mechanical brakes are less well understood. The small GTPase RhoA is a central regulator, activ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Bell, Kathryn Rehain, Werner, Michael E., Doshi, Anusha, Cortes, Daniel B., Sattler, Adam, Vuong-Brender, Thanh, Labouesse, Michel, Maddox, Amy Shaub
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521795/
https://ncbi.nlm.nih.gov/pubmed/32491957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-05-0304
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