Tumor necrosis factor receptor-associated factor 6 interaction with alpha-synuclein enhances cell death through the Nuclear Factor-kB pathway

BACKGROUND: Parkinson's disease (PD) is a neurodegenerative disease characterized by intracellular inclusions named Lewy bodies (LB), and alpha-synuclein (asyn) is the major component of these protein aggregates. The precise physiological and pathological roles of asyn are not fully understood....

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Vydáno v:IBRO Rep
Hlavní autoři: Yshii, Lidia M., Manfiolli, Adriana O., Denadai-Souza, Alexandre, Kinoshita, Paula F., Gomes, Marcelo D., Scavone, Cristoforo
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498709/
https://ncbi.nlm.nih.gov/pubmed/32984640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ibror.2020.08.005
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