Synthesis, anticancer evaluation and molecular docking studies of new benzimidazole- 1,3,4-oxadiazole derivatives as human topoisomerase types I poison

In this study, some benzimidazole-oxadiazole derivatives were synthesised and tested for their in vitro anticancer activities on five cancer cell lines, including HeLa, MCF7, A549, HepG2 and C6. Their structures were elucidated by IR, (1)H-NMR, (13)C-NMR, 2 D-NMR and HRMS spectroscopic methods. Amon...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Enzyme Inhib Med Chem
Egile Nagusiak: Acar Çevik, Ulviye, Sağlık, Begüm Nurpelin, Osmaniye, Derya, Levent, Serkan, Kaya Çavuşoğlu, Betül, Karaduman, Abdullah Burak, Atlı Eklioğlu, Özlem, Özkay, Yusuf, Kaplancıklı, Zafer Asım
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2020
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470102/
https://ncbi.nlm.nih.gov/pubmed/32811204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1806831
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