Synthesis and evaluation of a large library of nitroxoline derivatives as pancreatic cancer antiproliferative agents

Pancreatic cancer (PC) is one of the deadliest carcinomas and in most cases, which are diagnosed with locally advanced or metastatic disease, current therapeutic options are highly unsatisfactory. Based on the anti-proliferative effects shown by nitroxoline, an old urinary antibacterial agent, we ex...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Veschi, Serena, Carradori, Simone, De Lellis, Laura, Florio, Rosalba, Brocco, Davide, Secci, Daniela, Guglielmi, Paolo, Spano, Mattia, Sobolev, Anatoly P., Cama, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470072/
https://ncbi.nlm.nih.gov/pubmed/32588672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1780228
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