A comprehensive population-based study comparing the phenotype and genotype in a pretherapeutic screen of dihydropyrimidine dehydrogenase deficiency

BACKGROUND: Pretherapeutic screening for dihydropyrimidine dehydrogenase (DPD) deficiency is recommended or required prior to the administration of fluoropyrimidine-based chemotherapy. However, the best strategy to identify DPD-deficient patients remains elusive. METHODS: Among a nationwide cohort o...

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Publicat a:Br J Cancer
Autors principals: Pallet, Nicolas, Hamdane, Salma, Garinet, Simon, Blons, Hélène, Zaanan, Aziz, Paillaud, Elena, Taieb, Julien, Laprevote, Olivier, Loriot, Marie-Anne, Narjoz, Céline
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462856/
https://ncbi.nlm.nih.gov/pubmed/32595208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0962-z
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