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Design and Synthesis of Novel 1-hydroxy-2,4,5-triaryl Imidazole Derivatives as Anti-cytokine Agents

Among recent advances in the identification of anti-inflammation agents, anti-cytokines (like Interleukin-1), related to p38 MAPK families play an important role; Here in we designed new effective and low toxic anti-cytokine agents based on 1-hydroxy-2,4,5-triaryl imidazole derivatives. The reaction...

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Publicat a:Iran J Pharm Res
Autors principals: Haghighijoo, Zahra, Firuzi, Omidreza, Meili, Savis, Edraki, Najmeh, Khoshneviszadeh, Mehdi, Miri, Ramin
Format: Artigo
Idioma:Inglês
Publicat: Shaheed Beheshti University of Medical Sciences 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7462483/
https://ncbi.nlm.nih.gov/pubmed/32922479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22037/ijpr.2019.1100909
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