Human Lymph Node Stromal Cells Have the Machinery to Regulate Peripheral Tolerance during Health and Rheumatoid Arthritis

Background: In rheumatoid arthritis (RA) the cause for loss of tolerance and anti-citrullinated protein antibody (ACPA) production remains unidentified. Mouse studies showed that lymph node stromal cells (LNSCs) maintain peripheral tolerance through presentation of peripheral tissue antigens (PTAs)....

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Publié dans:Int J Mol Sci
Auteurs principaux: Hähnlein, Janine S., Nadafi, Reza, de Jong, Tineke A., Semmelink, Johanna F., Remmerswaal, Ester B. M., Safy, Mary, van Lienden, Krijn P., Maas, Mario, Gerlag, Danielle M., Tak, Paul P., Mebius, Reina E., Wähämaa, Heidi, Catrina, Anca I., G. M. van Baarsen, Lisa
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7460812/
https://ncbi.nlm.nih.gov/pubmed/32784936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165713
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